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2014年

  1. Gerstmann-Straeussler-Scheinker disease with P102L prion protein gene mutation presenting with rapidly progressive clinical course.

    Iwasaki Y, Mori K, Ito M, Nokura K, Tatsumi S, Mimuro M, Kitamoto T , Yoshida M.

    Clin Neuropathol. 2014 Jul 2. [Epub ahead of print]

  2. Extensive cortical spongiform changes with cerebellar small amyloid plaques: The clinicopathological case of MV2K+C subtype in Creutzfeldt-Jakob disease.

    Araki K, Nakano Y,  Kobayashi A , Matsudaira T, Sugiura A, Takao M, Kitamoto T , Murayama S, Obi T.

    Neuropathology. 2014 Jul 2. doi: 10.1111/neup.12133. [Epub ahead of print]

  3. Clinical features of genetic Creutzfeldt-Jakob disease with V180I mutation in the prion protein gene.

    Qina T, Sanjo N, Hizume M, Higuma M, Tomita M, Atarashi R, Satoh K, Nozaki I, Hamaguchi T, Nakamura Y,  Kobayashi A , Kitamoto T , Murayama S, Murai H, Yamada M, Mizusawa H.

    BMJ Open. 2014 May 16;4(5):e004968. doi: 10.1136/bmjopen-2014-004968.

  4. Aging and the mucosal immune system in the intestine.

    Mabbott NA,  Kobayashi A , Sehgal A, Bradford BM, Pattison M, Donaldson DS.

    Biogerontology. 2014 Apr 5. [Epub ahead of print]

  5. Distinct origins of dura mater graft-associated Creutzfeldt-Jakob disease: past and future problems.

     Kobayashi A , Matsuura Y,  Mohri S , Kitamoto T .

    Acta Neuropathol Commun. 2014 Mar 31;2(1):32. doi:10.1186/2051-5960-2-32.

  6. Creutzfeldt-jakob disease with a codon 210 mutation: first pathological observation in a Japanese patient.

    Tajima Y, Satoh C, Mito Y, Kitamoto T .

    Intern Med. 2014;53(5):483-7.

  7. Evaluating Prion Models Based on Comprehensive Mutation Data of Mouse PrP.

    Shirai T, Saito M, Kobayashi A , Asano M, Hizume M, Ikeda S, Teruya K, Morita M, Kitamoto T .

    Structure. 2014 Apr 8;22(4):560-71. doi: 10.1016/j.str.2013.12.019. Epub 2014 Feb 20.

  8. Molecular barriers to zoonotic transmission of prions.

    Barria MA, Balachandran A, Morita M, Kitamoto T , Barron R, Manson J, Knight R, Ironside JW, Head MW.

    Emerg Infect Dis. 2014 Jan;20(1):88-97. doi: 10.3201/eid2001.130858.

2013年

  1. Deciphering the Pathogenesis of Sporadic Creutzfeldt-Jakob Disease with Codon 129 M/V and Type 2 Abnormal Prion Protein

    Kobayashi A , Iwasaki S, Otsuka H, Yamada M, Yoshida M, Matsuura Y, Mohri S , Kitamoto T .

    Acta Neuropathol Commun. 2013 Nov 13;1(1):74. doi: 10.1186/2051-5960-1-74.

  2. Graft-related disease progression in dura mater graft-associated Creutzfeldt-Jakob disease: a cross-sectional study.

    Sakai K, Hamaguchi T, Noguchi-Shinohara M, Nozaki I, Takumi I, Sanjo N, Nakamura Y, Kitamoto T , Saito N, Mizusawa H, Yamada M.

    BMJ Open. 2013 Aug 23;3(8):e003400. doi: 10.1136/bmjopen-2013-003400.

  3. Critical Significance of the Region between Helix 1 and 2 for Efficient Dominant-Negative Inhibition by Conversion-Incompetent Prion Protein.

    Taguchi Y, Mistica AM,  Kitamoto T, Schätzl HM.

    PLoS Pathog. 2013 Jun;9(6):e1003466. Epub 2013 Jun 27.

  4. Characterization of variant Creutzfeldt-Jakob disease prions in prion protein-humanized mice carrying distinct codon 129 genotypes.

     Takeuchi A ,  Kobayashi A , Ironside JW,  Mohri S , Kitamoto T .

    J Biol Chem. J Biol Chem. 2013 July 26;288(30):21659-66. doi: 10.1074/jbc.M113.470328. Epub 2013 Jun 21.

  5. Insight into the frequent occurrence of dura mater graft-associated Creutzfeldt-Jakob disease in Japan.

    Hamaguchi T, Sakai K, Noguchi-Shinohara M, Nozaki I, Takumi I, Sanjo N, Sadakane A, Nakamura Y, Kitamoto T , Saito N, Mizusawa H, Yamada M.

    J Neurol Neurosurg Psychiatry. 2013 Oct;84(10):1171-5. doi: 10.1136/jnnp-2012-304850. Epub 2013 Apr 17.

  6. Relationships between clinicopathological features and cerebrospinal fluid biomarkers in Japanese patients with genetic prion diseases.

    Higuma M, Sanjo N, Satoh K, Shiga Y, Sakai K, Nozaki I, Hamaguchi T, Nakamura Y, Kitamoto T , Shirabe S, Murayama S, Yamada M, Tateishi J, Mizusawa H.

    PLoS One. 2013;8(3):e60003. doi: 10.1371/journal.pone.0060003. Epub 2013 Mar 28.

  7. Glycoform-selective prion formation in sporadic and familial forms of prion disease.

    Xiao X, Yuan J, Haïk S, Cali I, Zhan Y, Moudjou M, Li B, Laplanche JL, Laude H, Langeveld J, Gambetti P, Kitamoto T , Kong Q, Brandel JP, Cobb BA, Petersen RB, Zou WQ.

    PLoS One. 2013;8(3):e58786. doi: 10.1371/journal.pone.0058786. Epub 2013 Mar 19.

  8. Quantitative analysis of wet-heat inactivation in bovine spongiform encephalopathy.

    Matsuura Y, Ishikawa Y, Bo X, Murayama Y, Yokoyama T, Somerville RA, Kitamoto T,  Mohri S.

    Biochem Biophys Res Commun. 2013 Mar 1;432(1):86-91. doi: 10.1016/j.bbrc.2013.01.081. Epub 2013 Jan 30.

  9. The functional maturation of M cells is dramatically reduced in the Peyer's patches of aged mice.

    Kobayashi A , Donaldson DS, Erridge C, Kanaya T, Williams IR, Ohno H, Mahajan A, Mabbott NA.

    Mucosal Immunol. Mucosal Immunol. 2013 Sep;6(5):1027-37. doi: 10.1038/mi.2012.141. Epub 2013 Jan 30.

  10. An autopsied case of Creutzfeldt-Jakob disease with mutation in the prion protein gene codon 232 and type 1+2 prion protein.

    Iwasaki Y, Yokoi F, Tatsumi S, Mimuro M, Iwai K, Kitamoto T , Yoshida M.

    Neuropathology. 2013 Oct;33(5):568-75. doi: 10.1111/neup.12013. Epub 2013 Jan 16.

2012

  1. Identification of novel genes selectively expressed in the follicle-associated epithelium from the meta-analysis of transcriptomics data from multiple mouse cell and tissue populations.

    Kobayashi A , Donaldson DS, Kanaya T, Fukuda S, Baillie JK, Freeman TC, Ohno H, Williams IR, Mabbott NA.

    DNA Res. 2012 Oct;19(5):407-22. doi: 10.1093/dnares/dss022. Epub 2012 Sep 18.

  2. Enhanced antigen retrieval of amyloid β immunohistochemistry: re-evaluation of amyloid β pathology in Alzheimer disease and its mouse model.

    Kai H,Shin RW, Ogino K, Hatsuta H, Murayama S, Kitamoto T .

    J Histochem Cytochem. 2012 Oct;60(10):761-9. Epub 2012 Jul 21.

  3. M cell-depletion blocks oral prion disease pathogenesis.

    Donaldson DS, Kobayashi A , Ohno H, Yagita H, Williams IR, Mabbott NA.

    Mucosal Immunol. 2012 Mar;5(2):216-25. doi: 10.1038/mi.2011.68. Epub 2012 Feb 1.

  4. Creutzfeldt-Jakob disease with the M232R mutation in the prion protein gene in two cases showing different disease courses: a clinicopathological study.

    Takeda N, Yokota O, Terada S, Haraguchi T, Nobukuni K, Mizuki R, Honda H, Yoshida H, Kishimoto Y, Oshima E, Ishizu H, Satoh K, Kitamoto T , Ihara Y, Uchitomi Y.

    J Neurol Sci. 2012 Jan 15;312(1-2):108-16. doi: 10.1016/j.jns.2011.08.008. Epub 2011 Oct 7. Review.

2011

  1. Expression of mesenchyme-specific gene signatures by follicular dendritic cells: insights from the meta-analysis of microarray data from multiple mouse cell populations.

    Mabbott NA, Kenneth Baillie J, Kobayashi A , Donaldson DS, Ohmori H, Yoon SO, Freedman AS, Freeman TC, Summers KM.

    Immunology. 2011 Aug;133(4):482-98. doi: 10.1111/j.1365-2567.2011.03461.x. Epub 2011 Jun 3.

  2. Slow-progressive ataxia with a methionine-to-arginine point mutation in codon 232 in the prion protein gene (PRNP).

    Nishimoto Y, Ito D, Suzuki S, Shimizu T, Kitamoto T , Suzuki N.

    Clin Neurol Neurosurg. 2011 Oct;113(8):696-8. doi: 10.1016/j.clineuro.2011.04.009. Epub 2011 May 28. No abstract available.

  3. Heparin enhances the cell-protein misfolding cyclic amplification efficiency of variant Creutzfeldt-Jakob disease.

    Yokoyama T,  Takeuchi A, Yamamoto M, Kitamoto T , Ironside JW, Morita M.

    Neurosci Lett. 2011 Jul 8;498(2):119-23. doi: 10.1016/j.neulet.2011.04.072. Epub 2011 May 5.

  4. Deduction of the evaluation limit and termination timing of multi-round protein misfolding cyclic amplification from a titration curve.

     Takeuchi A, Komiya M, Kitamoto T , Morita M.

    Microbiol Immunol. 2011 Jul;55(7):502-9. doi: 10.1111/j.1348-0421.2011.00340.x.

  5. Co-occurrence of types 1 and 2 PrP(res) in sporadic Creutzfeldt-Jakob disease MM1.

     Kobayashi A, Mizukoshi K, Iwasaki Y, Miyata H, Yoshida Y, Kitamoto T.

    Am J Pathol. 2011 Mar;178(3):1309-15. doi: 10.1016/j.ajpath.2010.11.069.

  6. Ultrasensitive human prion detection in cerebrospinal fluid by real-time quaking-induced conversion.

    Atarashi R, Satoh K, Sano K, Fuse T, Yamaguchi N, Ishibashi D, Matsubara T, Nakagaki T, Yamanaka H, Shirabe S, Yamada M, Mizusawa H, Kitamoto T , Klug G, McGlade A, Collins SJ, Nishida N.

    Nat Med. 2011 Feb;17(2):175-8. doi: 10.1038/nm.2294. Epub 2011 Jan 30.

  7. An autopsied case of V180I Creutzfeldt-Jakob disease presenting with panencephalopathic-type pathology and a characteristic prion protein type.

    Iwasaki Y, Mori K, Ito M, Nagaoka M, Ieda T, Kitamoto T , Yoshida M, Hashizume Y.

    Neuropathology. 2011 Oct;31(5):540-8. doi: 10.1111/j.1440-1789.2010.01192.x. Epub 2011 Jan 27.

2010

  1. Actions of the Japanese Pancreas and Islet Transplantation Association regarding transplanted human islets isolated using Liberase HI.

    Saito T, Anazawa T, Gotoh M, Uemoto S, Kenmochi T, Kuroda Y, Satomi S, Itoh T, Yasunami Y, Kitamoto T , Mohri S, Teraoka S.

    Transplant Proc. 2010 Dec;42(10):4213-6. doi: 10.1016/j.transproceed.2010.09.142.

  2. Serial diffusion-weighted MRI and SPECT findings in a Creutzfeldt-Jakob disease patient with V180I mutation.

    Kono S, Manabe Y, Fujii D, Sakai Y, Narai H, Omori N, Kitamoto T , Abe K.

    J Neurol Sci. 2011 Feb 15;301(1-2):100-3. doi: 10.1016/j.jns.2010.10.032. Epub 2010 Nov 20.

  3. Prospective 10-year surveillance of human prion diseases in Japan.

    Nozaki I, Hamaguchi T, Sanjo N, Noguchi-Shinohara M, Sakai K, Nakamura Y, Sato T, Kitamoto T , Mizusawa H, Moriwaka F, Shiga Y, Kuroiwa Y, Nishizawa M, Kuzuhara S, Inuzuka T, Takeda M, Kuroda S, Abe K, Murai H, Murayama S, Tateishi J, Takumi I, Shirabe S, Harada M, Sadakane A, Yamada M.

    Brain. 2010 Oct;133(10):3043-57. doi: 10.1093/brain/awq216. Epub 2010 Sep 20.

  4. Shimizu Y, Kaku-Ushiki Y, Iwamaru Y, Muramoto T, Kitamoto T , Yokoyama T, Mohri S, Tagawa Y.

    Microbiol Immunol. 2010 Feb;54(2):112-21. doi: 10.1111/j.1348-0421.2009.00190.x.

  5. Experimental verification of a traceback phenomenon in prion infection.

     Kobayashi A, Sakuma N, Matsuura Y,  Mohri S, Aguzzi A, Kitamoto T .

    J Virol. 2010 Apr;84(7):3230-8. doi: 10.1128/JVI.02387-09. Epub 2010 Jan 20.

  6. Discordant clinicopathologic phenotypes in a Japanese kindred of fatal familial insomnia.

    Saitoh Y, Ogawa M, Naito Y, Komatsuzaki Y, Tagaya H, Arima K, Tamaoka A,Kitamoto T , Murata M.

    Neurology. 2010 Jan 5;74(1):86-9. doi: 10.1212/WNL.0b013e3181c7da09. No abstract available.

2009

  1. Age-dependent increase in lysosome-associated membrane protein 1 and early-onset behavioral deficits in APPSL transgenic mouse model of Alzheimer's disease.

    Hashimoto T, Ogino K,Shin RW, Kitamoto T , Kikuchi T, Shimizu N.

    Neurosci Lett. 2010 Jan 22;469(2):273-7. doi: 10.1016/j.neulet.2009.12.015. Epub 2009 Dec 16.

  2. Familial Creutzfeldt-Jakob disease with a V180I mutation: comparative analysis with pathological findings and diffusion-weighted images.

    Mutsukura K, Satoh K, Shirabe S, Tomita I, Fukutome T, Morikawa M, Iseki M, Sasaki K, Shiaga Y, Kitamoto T , Eguchi K.

    Dement Geriatr Cogn Disord. 2009;28(6):550-7. doi: 10.1159/000254842. Epub 2009 Dec 30.

  3. Amino acid conditions near the GPI anchor attachment site of prion protein for the conversion and the GPI anchoring.

    Hizume M,  Kobayashi A , Mizusawa H, Kitamoto T .

    Biochem Biophys Res Commun. 2010 Jan 22;391(4):1681-6. doi: 10.1016/j.bbrc.2009.12.128. Epub 2009 Dec 29.

  4. [Prion disease surveillance in Japan: analysis of 1,241 patients].

    Yamada M, Nozaki I, Hamaguchi T, Noguchi-Shinohara M, Kitamoto T , Nakamura Y, Sato T, Mizusawa H.

    Rinsho Shinkeigaku. 2009 Nov;49(11):939-42. Japanese.

  5. [History of 50 years of prion disease research].

    Kitamoto T .

    Rinsho Shinkeigaku. 2009 Nov;49(11):936-8. Japanese.

  6. Less protease-resistant PrP in a patient with sporadic CJD treated with intraventricular pentosan polysulphate.

    Terada T, Tsuboi Y, Obi T, Doh-ura K, Murayama S, Kitamoto T , Yamada T, Mizoguchi K.

    Acta Neurol Scand. 2010 Feb;121(2):127-30. doi: 10.1111/j.1600-0404.2009.01272.x. Epub 2009 Oct 5.

  7. An autopsy case of Creutzfeldt-Jakob disease with a V180I mutation of the PrP gene and Alzheimer-type pathology.

    Yoshida H, Terada S, Ishizu H, Ikeda K, Hayabara T, Ikeda K, Deguchi K, Touge T,Kitamoto T , Kuroda S.

    Neuropathology. 2010 Apr;30(2):159-64. doi: 10.1111/j.1440-1789.2009.01048.x. Epub 2009 Aug 23.

  8. Unique clinicopathological features and PrP profiles in the first autopsied case of dura mater graft-associated Creutzfeldt-Jakob disease with codon 219 lysine allele observed in Japanese population.

    Ikawa M, Yoneda M, Matsunaga A, Nakagawa H, Kazama-Suzuki A, Miyashita N, Naiki H, Kitamoto T , Kuriyama M.

    J Neurol Sci. 2009 Oct 15;285(1-2):265-7. doi: 10.1016/j.jns.2009.07.019. Epub 2009 Aug 8.

  9. The risk of iatrogenic Creutzfeldt-Jakob disease through medical and surgical procedures.

    Hamaguchi T, Noguchi-Shinohara M, Nozaki I, Nakamura Y, Sato T, Kitamoto T , Mizusawa H, Yamada M.

    Neuropathology. 2009 Oct;29(5):625-31. doi: 10.1111/j.1440-1789.2009.01023.x. Epub 2009 Jul 29. Review.

  10. A traceback phenomenon can reveal the origin of prion infection.

     Kobayashi A, Asano M, Mohri S, Kitamoto T .

    Neuropathology. 2009 Oct;29(5):619-24. doi: 10.1111/j.1440-1789.2008.00973.x. Epub 2009 Jul 29.

  11. Dura mater graft-associated Creutzfeldt-Jakob disease in Japan: clinicopathological and molecular characterization of the two distinct subtypes.

    Yamada M, Noguchi-Shinohara M, Hamaguchi T, Nozaki I, Kitamoto T , Sato T, Nakamura Y, Mizusawa H.

    Neuropathology. 2009 Oct;29(5):609-18. doi: 10.1111/j.1440-1789.2008.00987.x. Epub 2009 Jul 29.

  12. A case of Gerstmann-Sträussler-Scheinker syndrome with the P105L prion protein gene mutation presenting with ataxia and extrapyramidal signs without spastic paraparesis.

    Iwasaki Y, Kizawa M, Hori N, Kitamoto T , Sobue G.

    Clin Neurol Neurosurg. 2009 Sep;111(7):606-9. doi: 10.1016/j.clineuro.2009.03.008. Epub 2009 May 13.

  13. Creutzfeldt-Jakob disease with an M232R substitution: report of a patient showing slowly progressive disease with abundant plaque-like PrP deposits in the cerebellum.

    Shimizu H, Yamada M, Matsubara N, Takano H, Umeda Y, Kawase Y, Kitamoto T , Nishizawa M, Takahashi H.

    Neuropathology. 2009 Dec;29(6):735-43. doi: 10.1111/j.1440-1789.2009.01019.x. Epub 2009 Apr 21.

  14. An autopsied case of panencephalopathic-type Creutzfeldt-Jakob disease with mutation in the prion protein gene at codon 232 and type 1 prion protein.

    Hama T, Iwasaki Y, Niwa H, Yoshida M, Hashizume Y, Kitamoto T, Murakami N, Sobue G.

    Neuropathology. 2009 Dec;29(6):727-34. doi: 10.1111/j.1440-1789.2009.01016.x. Epub 2009 Apr 28.

  15. The first Japanese patient with variant Creutzfeldt-Jakob disease (vCJD).

    Shinde A, Kunieda T, Kinoshita Y, Wate R, Nakano S, Ito H, Yamada M, Kitamoto T, Nakamura Y, Matsumoto S, Kusaka H.

    Neuropathology. 2009 Dec;29(6):713-9. doi: 10.1111/j.1440-1789.2009.01006.x. Epub 2009 Mar 3.

  16. Heterozygous inhibition in prion infection: the stone fence model.

    Kobayashi A, Hizume M, Teruya K, Mohri S, Kitamoto T .

    Prion. 2009 Jan-Mar;3(1):27-30. Epub 2009 Jan 23. Review.

  17. The number of octapeptide repeat affects the expression and conversion of prion protein.

    Hiraga C, Kobayashi A, Kitamoto T .

    Biochem Biophys Res Commun. 2009 May 15;382(4):715-9. doi: 10.1016/j.bbrc.2009.03.093. Epub 2009 Mar 24.

  18. Medical procedures and risk for sporadic Creutzfeldt-Jakob disease, Japan, 1999-2008.

    Hamaguchi T, Noguchi-Shinohara M, Nozaki I, Nakamura Y, Sato T, Kitamoto T , Mizusawa H, Yamada M.

    Emerg Infect Dis. 2009 Feb;15(2):265-71.

  19. Coexistence of Creutzfeldt-Jakob disease, Lewy body disease, and Alzheimer's disease pathology: an autopsy case showing typical clinical features of Creutzfeldt-Jakob disease.

    Haraguchi T, Terada S, Ishizu H, Sakai K, Tanabe Y, Nagai T, Takata H, Nobukuni K, Ihara Y, Kitamoto T , Kuroda S.

    Neuropathology. 2009 Aug;29(4):454-9. doi: 10.1111/j.1440-1789.2008.00964.x. Review.

2008

  1. Human prion protein (PrP) 219K is converted to PrPSc but shows heterozygous inhibition in variant Creutzfeldt-Jakob disease infection.

    Hizume M, Kobayashi A , Teruya K, Ohashi H, Ironside JW, Mohri S, Kitamoto T .

    J Biol Chem. 2009 Feb 6;284(6):3603-9. doi: 10.1074/jbc.M809254200. Epub 2008 Dec 10.

  2. Plaque-type deposition of prion protein in the damaged white matter of sporadic Creutzfeldt-Jakob disease MM1 patients.

     Kobayashi A, Arima K, Ogawa M, Murata M, Fukuda T, Kitamoto T .

    Acta Neuropathol. 2008 Nov;116(5):561-6. doi: 10.1007/s00401-008-0425-8. Epub 2008 Aug 28.

  3. MM2-cortical-type sporadic Creutzfeldt-Jakob disease with early stage cerebral cortical pathology presenting with a rapidly progressive clinical course.

    Niimi Y, Iwasaki Y, Umemura T, Tanaka F, Yoshida M, Hashizume Y, Kitamoto T , Hirayama M, Sobue G.

    Neuropathology. 2008 Dec;28(6):645-51. doi: 10.1111/j.1440-1789.2008.00904.x. Epub 2008 Apr 10.

  4. [Case of Gerstmann-Sträussler-Scheinker syndrome (GSS-P102L) mimicking variant Creurtzfeldt-Jakob disease in clinical manifestation and MRI findings].

    Kanata A, Saigoh K, Mitsui Y, Kitamoto T , Kusunoki S.

    Rinsho Shinkeigaku. 2008 Mar;48(3):179-83. Japanese.

  5. Thr but Asn of the N-glycosylation sites of PrP is indispensable for its misfolding.

    Ikeda S,  Kobayashi A, Kitamoto T .

    Biochem Biophys Res Commun. 2008 May 16;369(4):1195-8. doi: 10.1016/j.bbrc.2008.03.014. Epub 2008 Mar 14.

  6. MM1-type sporadic Creutzfeldt-Jakob disease with unusually prolonged disease duration presenting with panencephalopathic-type pathology.

    Hoshino A, Iwasaki Y, Izumi M, Kimura S, Ibi T, Kitamoto T , Yoshida M, Hashizume Y, Sahashi K.

    Neuropathology. 2008 Jun;28(3):326-32. doi: 10.1111/j.1440-1789.2007.00854.x. Epub 2008 Feb 1.

  7. Clinicopathologic characteristics of five autopsied cases of dura mater-associated Creutzfeldt-Jakob disease.

    Iwasaki Y, Mimuro M, Yoshida M, Hashizume Y, Kitamoto T , Sobue G.

    Neuropathology. 2008 Feb;28(1):51-61. doi: 10.1111/j.1440-1789.2007.00847.x.

1983-2007

  1. Iwasaki Y, Yoshida M, Hashizume Y, Kitamoto T, Sobue G: Pyramidal tract degeneration in sporadic Creutzfeldt-Jakob disease. Neuropathology. 2007; 27: 434-441.
  2. Iwasaki Y, Mimuro M, Yoshida M, Hashizume Y, Ito M, Kitamoto T, Wakayama Y, Sobue G: Enhanced Aquaporin-4 immunoreactivity in sporadic Creutzfeldt-Jakob disease. Neuropathology. 2007; 27: 314-323.
  3. Shiga Y, Satoh K, Kitamoto T, Kanno S, Nakashima I, Sato S, Fujihara K, Takata H, Nobukuni K, Kuroda S, Takano H, Umeda Y, Konno H, Nagasato K, Satoh A, Matsuda Y, Hidaka M, Takahashi H, Sano Y, Kim K, Konishi T, Doh-ura K, Sato T, Sasaki K, Nakamura Y, Yamada M, Mizusawa H, Itoyama Y.Two different clinical phenotypes of Creutzfeldt-Jakob disease with a M232R substitution.J Neurol. 2007 Nov;254(11):1509-17. Epub 2007 Nov 2.
  4. Kobayashi A, Asano M, Mohri S, Kitamoto T. Cross-sequence transmission of sporadic Creutzfeldt-Jakob disease creates a new prion strain. J Biol Chem. 2007; 282: 30022-30028
  5. Hamaguchi T, Noguchi-Shinohara M, Nakamura Y, Sato T, KitamotoT,Mizusawa H, Yamada M. Ophthalmic surgery in prion diseases.Emerg Infect Dis. 2007 Jan;13(1):162-4.
  6. Shin RW, Ogino K, Shimabuku A, Taki T, Nakashima H, Ishihara T, KitamotoT. Amyloid precursor protein cytoplasmic domainwithphospho-Thr668accumulates inAlzheimer's disease and its transgenic models: a role tomediate interaction of Abeta and tau.Acta Neuropathol (Berl). 2007 Jun;113(6):627-36.
  7. Noguchi-Shinohara M, Hamaguchi T, Kitamoto T, Sato T, Nakamura Y,Mizusawa H, Yamada M.Clinical features and diagnosis of dura mater graft associatedCreutzfeldt Jakob disease.Neurology. 2007 Jul 24;69(4):360-7.
  8. Iwasaki Y, Iijima M, Kimura S, Yoshida M, Hashizume Y, Yamada M, Kitamoto T, Sobue G. Autopsy case of sporadic Creutzfeldt-Jakob disease presenting with signs suggestive of brainstem and spinal cord involvement. Neuropathology. 2006 Dec;26(6):550-6.
  9. Iwasaki Y, Yoshida M, Hashizume Y, Kitamoto T, Sobue G.  Clinicopathologic characteristics of sporadic Japanese Creutzfeldt-Jakob disease classified according to prion protein gene polymorphism and prion protein type.Acta Neuropathol (Berl).  2006 Nov;112(5):561-71. Epub 2006 Jul 18.
  10. Hirose K, Iwasaki Y, Izumi M, Yoshida M, Hashizume Y, Kitamoto T, Sahashi K.  MM2-thalamic-type sporadic Creutzfeldt-Jakob disease with widespread neocortical pathology.Acta Neuropathol (Berl).  2006 Oct;112(4):503-11. Epub 2006 Sep 7.
  11. Ishihara K, Sugie M, Shiota J, Kawamura M, Kitamoto T, Nakano I.  Severe cortical involvement in MV2 Creutzfeldt-Jakob disease: an autopsy case report.Neuropathology. 2006 Oct;26(5):433-7.
  12. Kawauchi Y, Kamitani T, Yagishita S, Kitamoto T, Kishida H.  Autopsy case of Creutzfeldt-Jakob disease with Met/Val heterozygosity at codon 129 and type 1 protease-resistant prion protein presenting some florid-type plaques and many Kuru plaques in the cerebellum.Neuropathology.  2006 Aug;26(4):313-7.
  13. Asano M, Mohri S, Ironsido JW, Ito M, Tamaoki N, Kitamoto T.vCJD prion acquires altered virulence through trans-species infection.Biochem Biophys Res Commun. 2006 Mar 31;342(1):293-9. Epub 2006 Feb 7.PMID: 16480953
  14. Wakisaka Y, Santa N, Dho-ura K, Kitamoto T, Ibayashi S, Iida M, Iwaki T.Increased asymmetric pulvinar magnetic resonance imaging signals in Creutzfeldt-Jakob disease with florid plaques following a cadaveric dura mater graft.Neuropathology. 2006 Feb;26(1):82-8.PMID: 16521484
  15. Iwasaki Y, Yoshida M, Hashizume Y, Kitamoto T, Sobue G.Neuropathologic characteristics of spinal cord lesions in sporadic Creutzfeldt-Jakob disease.Acta Neuropathol (Berl). 2005 Nov;110(5):490-500. Epub 2005 Sep 21.PMID: 16175355
  16. Akiyama H, Shin RW, Uchida C, Kitamoto T, Uchida T.Pin1 promotes production of Alzheimer's amyloid beta from beta-cleaved amyloid precursor protein.Biochem Biophys Res Commun. 2005 Oct 21;336(2):521-9.PMID: 16139797
  17. Iwasaki Y, Hashizume Y, Yoshida M, Kitamoto T, Sobue G.Neuropathologic characteristics of brainstem lesions in sporadic Creutzfeldt-Jakob disease.Acta Neuropathol (Berl). 2005 Jun;109(6):557-66. Epub 2005 Jun 3.PMID: 15933870
  18. Piao YS, Kakita A, Watanabe H, Kitamoto T, Takahashi H.Sporadic fatal insomnia with spongiform degeneration in the thalamus and widespread PrPSc deposits in the brain.Neuropathology. 2005 Jun;25(2):144-9. PMID: 15875907
  19. Shin RW, Saido TC, Maeda M, Kitamoto T.Novel alpha-secretase cleavage of Alzheimer's amyloid beta precursor protein in the endoplasmic reticulum of COS7 cells.Neurosci Lett. 2005 Mar 7;376(1):14-9. Epub 2004 Dec 8.PMID: 15694266
  20. Ishida C, Okino S, Kitamoto T, Tamada M.Involvement of the peripheral nervous system in human prion diseases including dural graft associated Creutzfeldt-Jakob disease.J Neurol Neurosurg Psychiatry. 2005 Mar;76(3):325-9.PMID: 15716520
  21. Hamaguchi T,Kitamoto T, Sato T, Mizusawa H, Nakamura Y, Noguchi M, Furukawa Y, Ishida C, Kuji I, Mitani K, Murayama S, Kohriyama T, Katayama S, Yamashita M, Yamamoto T, Udaka F, Kawakami A, Ihara Y, Nishinaka T, Kuroda S, Suzuki N, Shiga Y, Arai H, Maruyama M, Yamada M.Clinical diagnosis of MM2-type sporadic Creutzfeldt-Jakob disease.Neurology. 2005 Feb 22;64(4):643-8. Review.PMID: 15728285
  22. Kobayashi A, Satoh S, Ironside JW, Mohri S, Kitamoto T.Type 1 and type 2 human PrPSc have different aggregation sizes in methionine homozygotes with sporadic, iatrogenic and variant Creutzfeldt-Jakob disease.J Gen Virol. 2005 Jan;86(Pt 1):237-40. PMID: 15604452
  23. Ishida C, Okino S, Kitamoto T, Yamada M. Involvement of the peripheral nervous system in human prion diseases including dural graft associated Creutzfeldt-Jakob disease.J Neurol Neurosurg Psychiatry. 2005 Mar;76(3):325-9.
  24. Tanaka T, Kinoshita I, Saitoh Y, Satoh K, Nishiura Y, Shirabe S, Kitamoto T. [A case of Creutzfeldt-Jakob disease with a point mutation of prion protein at codon 180] No To Shinkei.2004 Dec;56(12):1025-8.Review.Japanese.
  25. Kobayashi A, Satoh S, Ironside JW, Mohri S, Kitamoto T. Type1 and Type2 human PrPSc have different aggregation sizes in methionine homozygotes with sporadic, iatrogenic and variant Creutzfeldt-Jakob disease. J Gen Virol. 2005 Jan;86(Pt1):237-40.
  26. Satoh K, Shirabe S, Katamine S, Muramoto T, Kitamoto T. [Iatrogenic Creutzfeldt-Jakob disease] Nippon Rinsho. 2004 Jan;62 Suppl:248-51. Review. Japanese.
  27. Fukushima R, Shiga Y, Nakamura M, Fujimori J, Kitamoto T, Yoshida Y. MRI characteristics of sporadic CJD with valine homozygosity at codon 129 of the prion protein gene and PrPSc type 2 in Japan. J Neurol Neurosurg Psychiatry. 2004 Mar;75(3):485-7.
  28. Jin K, Shiga Y, Shibuya S, Chida K, Sato Y, Konno H, Doh-ura K, Kitamoto T, Itoyama Y. Clinical features of Creutzfeldt-Jakob disease with V180I mutation. Neurology. 2004 Feb;62(3):502-5.
  29. Taguchi Y, Mohri S, Ironside JW, Muramoto T, Kitamoto T. Humanized knock-in mice expressing chimeric prion protein showed varied susceptibility to different human prions. Am J Pathol. 2003 Dec;163(6):2585-93.
  30. Nakamura N, Miyamoto K, Shimokawa M, Nishida N, Mohri S, Kitamoto T, Horiuchi H, Furusawa S, Matsuda H. Generation of antibodies against prion protein by scrapie-infected cell immunization of PrP(0/0) mice. Hybrid Hybridomics. 2003 Aug;22(4):263-6.
  31. Satoh K, Muramoto T, Tanaka T, Kitamoto N, Ironside JW, Nagashima K, Yamada M, Sato T, Mohri S, Kitamoto T. Association of an 11-12 kDa protease-resistant prion protein fragment with subtypes of dura graft-associated Creutzfeldt-Jakob disease and other prion diseases. J Gen Virol. 2003 Oct;84(Pt 10):2885-93.
  32. Mochizuki Y, Mizutani T, Tajiri N, Oinuma T, Nemoto N, Kakimi S, Kitamoto T. Creutzfeldt-Jakob disease with florid plaques after cadaveric dura mater graft. Neuropathology. 2003 Jun;23(2):136-40.
  33. Gombojav A, Shimauchi I, Horiuchi M, Ishiguro N, Shinagawa M, Kitamoto T, Miyoshi I, Mohri S, Takata M. Susceptibility of transgenic mice expressing chimeric sheep, bovine and human PrP genes to sheep scrapie. J Vet Med Sci. 2003 Mar;65(3):341-7.
  34. Shimamura M, Uyama E, Hirano T, Murakami T, Mita S, Kitamoto T, Uchino M. A unique case of sporadic Creutzfeldt-Jacob disease presenting as progressive supranuclear palsy. Intern Med. 2003 Feb;42(2):195-8.
  35. Yamamoto S, Furukawa H, Kitamoto T, Takamaru Y, Morita N, Yasuda M, Okada Y, Sawa H, Nagashima K. An atypical form of sporadic panencephalopathic Creutzfeldt-Jakob disease in Japan. Neuropathol Appl Neurobiol. 2003 Feb;29(1):77-80.
  36. Ishida C, Kakishima A, Okino S, Furukawa Y, Kano M, Oda Y, Nakanishi I, Makifuchi T, Kitamoto T, Yamada M. Sporadic Creutzfeldt-Jakob disease with MM1-type prion protein and plaques. Neurology. 2003 Feb 11;60(3):514-7.
  37. Shin RW, Kruck TP, Murayama H, Kitamoto T. A novel trivalent cation chelator Feralex dissociates binding of aluminum and iron associated with hyperphosphorylated tau of Alzheimer's disease. Brain Res. 2003 Jan 24;961(1):139-46.
  38. Yamamoto A, Shin RW, Hasegawa K, Naiki H, Sato H, Yoshimasu F, Kitamoto T. Iron (III) induces aggregation of hyperphosphorylated tau and its reduction to iron (II) reverses the aggregation: implications in the formation of neurofibrillary tangles of Alzheimer's disease. J Neurochem. 2002 Sep;82(5):1137-47.
  39. Kitamoto T. [Prion diseases, update] Rinsho Shinkeigaku. 2001 Dec;41(12):1223-5.
  40. Ishizawa K, Komori T, Shimazu T, Yamamoto T, Kitamoto T, Shimazu K, Hirose T. Hyperphosphorylated tau deposition parallels prion protein burden in a case of Gerstmann-Straussler-Scheinker syndrome P102L mutation complicated with dementia. Acta Neuropathol (Berl). 2002 Oct;104(4):342-50.
  41. Sasaki N, Takeuchi M, Chowei H, Kikuchi S, Hayashi Y, Nakano N, Ikeda H, Yamagishi S, Kitamoto T, Saito T, Makita Z. Advanced glycation end products (AGE) and their receptor (RAGE) in the brain of patients with Creutzfeldt-Jakob disease with prion plaques. Neurosci Lett. 2002 Jun 28;326(2):117-20.
  42. Kitamoto T, Mohri S, Ironside JW, Miyoshi I, Tanaka T, Kitamoto N, Itohara S, Kasai N, Katsuki M, Higuchi J, Muramoto T, Shin RW. Follicular dendritic cell of the knock-in mouse provides a new bioassay for human prions. Biochem Biophys Res Commun. 2002 Jun 7;294(2):280-6.
  43. Tateishi J, Kitamoto T, Mohri S, Satoh S, Sato T, Shepherd A, Macnaughton MR. Scrapie removal using Planova virus removal filters. Biologicals. 2001 Mar;29(1):17-25.
  44. Yamashita M, Yamamoto T, Nishinaka K, Udaka F, Kameyama M, Kitamoto T. Severe brain atrophy in a case of thalamic variant of sporadic CJD with plaque-like PrP deposition. Neuropathology. 2001 Jun;21(2):138-43.
  45. Kitamoto T. [Prion diseases] Nippon Ronen Igakkai Zasshi. 2000 Oct;37(10):780-1. Japanese.
  46. Nakamura Y, Oki I, Tanihara S, Ojima T, Yanagawa H, Kitamoto T, Sato T. A case-control study of Creutzfeldt-Jakob disease in Japan: transplantation of cadaveric dura mater was a risk factor. J Epidemiol. 2000 Nov;10(6):399-402.
  47. Konaka K, Kaido M, Okuda Y, Aoike F, Abe K, Kitamoto T, Yanagihara T. Proton magnetic resonance spectroscopy of a patient with Gerstmann-Straussler-Scheinker disease. Neuroradiology. 2000 Sep;42(9):662-5.
  48. Nakamura Y, Yanagawa H, Kitamoto T, Sato T. Epidemiologic features of 65 Creutzfeldt-Jakob disease patients with a history of cadaveric dura mater transplantation in Japan. Epidemiol Infect. 2000 Aug;125(1):201-5.
  49. Kitamoto T. Creutzfeldt-Jakob disease. Neuropathology. 2000 Sep;20 Suppl:S52-4. Review.
  50. Muramoto T, Tanaka T, Kitamoto N, Sano C, Hayashi Y, Kutomi T, Yutani C, Kitamoto T. Analyses of Gerstmann-Straussler syndrome with 102Leu219Lys using monoclonal antibodies that specifically detect human prion protein with 219Glu. Neurosci Lett. 2000 Jul 21;288(3):179-82.
  51. Yamazaki M, Oyanagi K, Mori O, Kitamura S, Ohyama M, Terashi A, Kitamoto T, Katayama Y. Variant Gerstmann-Straussler syndrome with the P105L prion gene mutation: an unusual case with nigral degeneration and widespread neurofibrillary tangles. Acta Neuropathol (Berl). 1999 Nov;98(5):506-11.
  52. Murayama H, Shin RW, Higuchi J, Shibuya S, Muramoto T, Kitamoto T. Interaction of aluminum with PHFtau in Alzheimer's disease neurofibrillary degeneration evidenced by desferrioxamine-assisted chelating autoclave method. Am J Pathol. 1999 Sep;155(3):877-85.
  53. Yamada M, Itoh Y, Inaba A, Wada Y, Takashima M, Satoh S, Kamata T, Okeda R, Kayano T, Suematsu N, Kitamoto T, Otomo E, Matsushita M, Mizusawa H. An inherited prion disease with a PrP P105L mutation: clinicopathologic and PrP heterogeneity. Neurology. 1999 Jul 13;53(1):181-8. Review.
  54. Nagaoka U, Kurita K, Hosoya T, Kitamoto T, Kato T. [Diffusion images on brain MRI in Creutzfeldt-Jakob disease] Rinsho Shinkeigaku. 1999 Apr;39(4):468-70. Japanese.
  55. Nagashima T, Okawa M, Kitamoto T, Takahashi H, Ishihara Y, Ozaki Y, Nagashima K. Wernicke encephalopathy-like symptoms as an early manifestation of Creutzfeldt-Jakob disease in a chronic alcoholic. J Neurol Sci. 1999 Mar 1;163(2):192-8.
  56. Hainfellner JA, Parchi P, Kitamoto T, Jarius C, Gambetti P, Budka H. A novel phenotype in familial Creutzfeldt-Jakob disease: prion protein gene E200K mutation coupled with valine at codon 129 and type 2 protease-resistant prion protein. Ann Neurol. 1999 Jun;45(6):812-6.
  57. Iino K, Sasano H, Oki Y, Andoh N, Shin RW, Kitamoto T, Takahashi K, Suzuki H, Tezuka F, Yoshimi T, Nagura H. Urocortin expression in the human central nervous system. Clin Endocrinol (Oxf). 1999 Jan;50(1):107-14.
  58. Matsuda H, Mitsuda H, Nakamura N, Furusawa S, Mohri S, Kitamoto T. A chicken monoclonal antibody with specificity for the N-terminal of human prion protein. FEMS Immunol Med Microbiol. 1999 Mar;23(3):189-94.
  59. Shimizu S, Hoshi K, Muramoto T, Homma M, Ironside JW, Kuzuhara S, Sato T, Yamamoto T, Kitamoto T. Creutzfeldt-Jakob disease with florid-type plaques after cadaveric dura mater grafting. Arch Neurol. 1999 Mar;56(3):357-62. Review.
  60. Shibuya S, Higuchi J, Shin RW, Tateishi J, Kitamoto T. Codon 219 Lys allele of PRNP is not found in sporadic Creutzfeldt-Jakob disease. Ann Neurol. 1998 Jun;43(6):826-8.
  61. Shibuya S, Higuchi J, Shin RW, Tateishi J, Kitamoto T. Protective prion protein polymorphisms against sporadic Creutzfeldt-Jakob disease. Lancet. 1998 Feb 7;351(9100):419.
  62. Iino K, Sasano H, Oki Y, Andoh N, Shin RW, Kitamoto T, Totsune K, Takahashi K, Suzuki H, Nagura H, Yoshimi T. Urocortin expression in human pituitary gland and pituitary adenoma. J Clin Endocrinol Metab. 1997 Nov;82(11):3842-50.
  63. Shin RW, Ogino K, Kondo A, Saido TC, Trojanowski JQ, Kitamoto T, Tateishi J. Amyloid beta-protein (Abeta) 1-40 but not Abeta1-42 contributes to the experimental formation of Alzheimer disease amyloid fibrils in rat brain. J Neurosci. 1997 Nov 1;17(21):8187-93.
  64. Tanaka Y, Minematsu K, Moriyasu H, Yamaguchi T, Yutani C, Kitamoto T, Furukawa H. A Japanese family with a variant of Gerstmann-Straussler-Scheinker disease. J Neurol Neurosurg Psychiatry. 1997 May;62(5):454-7.
  65. Parchi P, Capellari S, Chen SG, Petersen RB, Gambetti P, Kopp N, Brown P, Kitamoto T, Tateishi J, Giese A, Kretzschmar H. Typing prion isoforms. Nature. 1997 Mar 20;386(6622):232-4.
  66. Kawasaki K, Wakabayashi K, Kawakami A, Higuchi M, Kitamoto T, Tsuji S, Takahashi H. Thalamic form of Creutzfeldt-Jakob disease or fatal insomnia? Report of a sporadic case with normal prion protein genotype. Acta Neuropathol (Berl). 1997 Mar;93(3):317-22.
  67. Hitotsumatsu T, Iwaki T, Kitamoto T, Mizoguchi M, Suzuki SO, Hamada Y, Fukui M, Tateishi J. Expression of neurofibromatosis 2 protein in human brain tumors: an immunohistochemical study. Acta Neuropathol (Berl). 1997 Mar;93(3):225-32.
  68. Doh-ura K, Kitamoto T. [Prion diseases and a new variant of Creutzfeldt-Jakob disease] Rinsho Shinkeigaku. 1996 Dec;36(12):1370-2. Japanese.
  69. Obi T, Takatsu M, Kitamoto T, Mizoguchi K, Nishimura Y. [A case of Creutzfeldt-Jakob disease (CJD) started with monoparesis of the left arm] Rinsho Shinkeigaku. 1996 Nov;36(11):1245-8. Japanese.
  70. Tateishi J, Kitamoto T, Kretzschmar H, Mehraein P. Immunhistological evaluation of Creutzfeldt-Jakob disease with reference to the type PrPres deposition. Clin Neuropathol. 1996 Nov-Dec;15(6):358-60.
  71. Hoque MZ, Kitamoto T, Furukawa H, Muramoto T, Tateishi J. Mutation in the prion protein gene at codon 232 in Japanese patients with Creutzfeldt-Jakob disease: a clinicopathological, immunohistochemical and transmission study. Acta Neuropathol (Berl). 1996 Nov;92(5):441-6.
  72. Nagayama M, Shinohara Y, Furukawa H, Kitamoto T. Fatal familial insomnia with a mutation at codon 178 of the prion protein gene: first report from Japan. Neurology. 1996 Nov;47(5):1313-6.
  73. Furukawa H, Kitamoto T, Hashiguchi H, Tateishi J. A Japanese case of Creutzfeldt-Jakob disease with a point mutation in the prion protein gene at codon 210. J Neurol Sci. 1996 Sep 15;141(1-2):120-2.
  74. Kitamoto T, Nakamura K, Nakao K, Shibuya S, Shin RW, Gondo Y, Katsuki M, Tateishi J. Humanized prion protein knock-in by Cre-induced site-specific recombination in the mouse. Biochem Biophys Res Commun. 1996 May 24;222(3):742-7.
  75. Kitamoto T. [Prion diseases in dementia] Nippon Ronen Igakkai Zasshi. 1996 Mar;33(3):178-9. Japanese.
  76. Tateishi J, Kitamoto T, Hoque MZ, Furukawa H. Experimental transmission of Creutzfeldt-Jakob disease and related diseases to rodents. Neurology. 1996 Feb;46(2):532-7.
  77. Ghetti B, Piccardo P, Spillantini MG, Ichimiya Y, Porro M, Perini F, Kitamoto T, Tateishi J, Seiler C, Frangione B, Bugiani O, Giaccone G, Prelli F, Goedert M, Dlouhy SR, Tagliavini F. Vascular variant of prion protein cerebral amyloidosis with tau-positive neurofibrillary tangles: the phenotype of the stop codon 145 mutation in PRNP. Proc Natl Acad Sci U S A. 1996 Jan 23;93(2):744-8.
  78. Kitamoto T, Tateishi J. Human prion disease and human prion protein disease. Curr Top Microbiol Immunol. 1996;207:27-34. Review.
  79. Yasuyama K, Kitamoto T, Salvaterra PM. Localization of choline acetyltransferase-expressing neurons in the larval visual system of Drosophila melanogaster. Cell Tissue Res. 1995 Nov;282(2):193-202.
  80. Ishida S, Sugino M, Koizumi N, Shinoda K, Ohsawa N, Ohta T, Kitamoto T, Tateishi J. Serial MRI in early Creutzfeldt-Jacob disease with a point mutation of prion protein at codon 180. Neuroradiology. 1995 Oct;37(7):531-4.
  81. Tateishi J, Brown P, Kitamoto T, Hoque ZM, Roos R, Wollman R, Cervenakova L, Gajdusek DC. First experimental transmission of fatal familial insomnia. Nature. 1995 Aug 3;376(6539):434-5.
  82. Hainfellner JA, Brantner-Inthaler S, Cervenakova L, Brown P, Kitamoto T, Tateishi J, Diringer H, Liberski PP, Regele H, Feucht M, et al. The original Gerstmann-Straussler-Scheinker family of Austria: divergent clinicopathological phenotypes but constant PrP genotype. Brain Pathol. 1995 Jul;5(3):201-11.
  83. Furukawa H, Kitamoto T, Tanaka Y, Tateishi J. New variant prion protein in a Japanese family with Gerstmann-Straussler syndrome. Brain Res Mol Brain Res. 1995 Jun;30(2):385-8.
  84. Nakagawa Y, Kitamoto T, Furukawa H, Ogomori K, Tateishi J. Allelic variation of apolipoprotein E in Japanese sporadic Creutzfeldt-Jakob disease patients. Neurosci Lett. 1995 Mar 10;187(3):209-11.
  85. Matsumura T, Kojima S, Kuroiwa Y, Takagi A, Unakami M, Kitamoto T. [An autopsy-verified case of Creutzfeldt-Jakob disease with codon 129 polymorphism and codon 180 point mutation] Rinsho Shinkeigaku. 1995 Mar;35(3):282-5. Japanese.
  86. Nakagawa Y, Kitamoto T, Furukawa H, Ogomori K, Tateishi J. Apolipoprotein E in Creutzfeldt-Jakob disease. Lancet. 1995 Jan 7;345(8941):68.
  87. Tateishi J, Kitamoto T. Inherited prion diseases and transmission to rodents. Brain Pathol. 1995 Jan;5(1):53-9. Review.
  88. Oda T, Kitamoto T, Tateishi J, Mitsuhashi T, Iwabuchi K, Haga C, Oguni E, Kato Y, Tominaga I, Yanai K, et al. Prion disease with 144 base pair insertion in a Japanese family line. Acta Neuropathol (Berl). 1995;90(1):80-6.
  89. Ohta M, Iwaki T, Kitamoto T, Takeshita I, Tateishi J, Fukui M. MIB1 staining index and scoring of histologic features in meningioma. Indicators for the prediction of biologic potential and postoperative management. Cancer. 1994 Dec 15;74(12):3176-89.
  90. Kitamoto T. [Molecular genetics in Creutzfeldt-Jakob disease] Rinsho Shinkeigaku. 1994 Dec;34(12):1222-3. Review. Japanese.
  91. Hitotsumatsu T, Kitamoto T, Iwaki T, Fukui M, Tateishi J. An exon 8-spliced out transcript of neurofibromatosis 2 gene is constitutively expressed in various human tissues. J Biochem (Tokyo). 1994 Dec;116(6):1205-7.
  92. Itoh Y, Yamada M, Hayakawa M, Shozawa T, Tanaka J, Matsushita M, Kitamoto T, Tateishi J, Otomo E. A variant of Gerstmann-Straussler-Scheinker disease carrying codon 105 mutation with codon 129 polymorphism of the prion protein gene: a clinicopathological study. J Neurol Sci. 1994 Dec 1;127(1):77-86. Review.
  93. Hara H, Morita M, Iwaki T, Hatae T, Itoyama Y, Kitamoto T, Akizuki S, Goto I, Watanabe T. Detection of human T lymphotrophic virus type I (HTLV-I) proviral DNA and analysis of T cell receptor V beta CDR3 sequences in spinal cord lesions of HTLV-I-associated myelopathy/tropical spastic paraparesis. J Exp Med. 1994 Sep 1;180(3):831-9.
  94. Yu F, Itoyama Y, Kira J, Fujihara K, Kobayashi T, Kitamoto T, Suzumura A, Yamamoto N, Nakajima Y, Goto I. TNF-beta produced by human T lymphotropic virus type I-infected cells influences the proliferation of human endothelial cells and fibroblasts. J Immunol. 1994 Jun 15;152(12):5930-8.
  95. Shimizu T, Tanaka K, Tanahashi N, Fukuuchi Y, Kitamoto T. [Creutzfeldt-Jakob disease with a point mutation at codon 232 of prion protein--a case report] Rinsho Shinkeigaku. 1994 Jun;34(6):590-2. Japanese.
  96. Yamada S, Aiba T, Endo Y, Hara M, Kitamoto T, Tateishi J. Creutzfeldt-Jakob disease transmitted by a cadaveric dura mater graft. Neurosurgery. 1994 Apr;34(4):740-3; discussion 743-4. Review.
  97. Kitamoto T, Tateishi J. Human prion diseases with variant prion protein. Philos Trans R Soc Lond B Biol Sci. 1994 Mar 29;343(1306):391-8.
  98. Inoue I, Kitamoto T, Doh-ura K, Shii H, Goto I, Tateishi J. Japanese family with Creutzfeldt-Jakob disease with codon 200 point mutation of the prion protein gene. Neurology. 1994 Feb;44(2):299-301.
  99. Doi-Yi R, Kitamoto T, Ogomori K, Mehraein P, Tateishi J. Distribution of prion protein in German patients with Creutzfeldt-Jakob disease is different from that in Japanese patients. Acta Neuropathol (Berl). 1994;87(5):481-3.
  100. Hitoshi S, Nagura H, Yamanouchi H, Kitamoto T. Double mutations at codon 180 and codon 232 of the PRNP gene in an apparently sporadic case of Creutzfeldt-Jakob disease. J Neurol Sci. 1993 Dec 15;120(2):208-12.
  101. Kitamoto T, Amano N, Terao Y, Nakazato Y, Isshiki T, Mizutani T, Tateishi J. A new inherited prion disease (PrP-P105L mutation) showing spastic paraparesis. Ann Neurol. 1993 Dec;34(6):808-13.
  102. Yamada M, Itoh Y, Fujigasaki H, Naruse S, Kaneko K, Kitamoto T, Tateishi J, Otomo E, Hayakawa M, Tanaka J, et al. A missense mutation at codon 105 with codon 129 polymorphism of the prion protein gene in a new variant of Gerstmann-Straussler-Scheinker disease. Neurology. 1993 Dec;43(12):2723-4.
  103. Muramoto T, Kitamoto T, Tateishi J, Goto I. Accumulation of abnormal prion protein in mice infected with Creutzfeldt-Jakob disease via intraperitoneal route: a sequential study. Am J Pathol. 1993 Nov;143(5):1470-9.
  104. Muramoto T, Kitamoto T, Hoque MZ, Tateishi J, Goto I. Species barrier prevents an abnormal isoform of prion protein from accumulating in follicular dendritic cells of mice with Creutzfeldt-Jakob disease. J Virol. 1993 Nov;67(11):6808-10.
  105. Ohgami T, Kitamoto T, Tateishi J. Alzheimer's amyloid precursor protein mRNA without exon 15 is ubiquitously expressed except in the rat central nervous system. Brain Res Mol Brain Res. 1993 Nov;20(3):240-4.
  106. Ohta M, Kitamoto T, Iwaki T, Ohgami T, Fukui M, Tateishi J. Immunohistochemical distribution of amyloid precursor protein during normal rat development. Brain Res Dev Brain Res. 1993 Oct 15;75(2):151-61.
  107. Ohgami T, Kitamoto T, Tateishi J. The rat central nervous system expresses Alzheimer's amyloid precursor protein APP695, but not APP677 (L-APP form). J Neurochem. 1993 Oct;61(4):1553-6.
  108. Tada S, Iida M, Yao T, Kitamoto T, Yao T, Fujishima M. Intestinal pseudo-obstruction in patients with amyloidosis: clinicopathologic differences between chemical types of amyloid protein. Gut. 1993 Oct;34(10):1412-7.
  109. Tateishi J, Kitamoto T. Developments in diagnosis for prion diseases. Br Med Bull. 1993 Oct;49(4):971-9. Review.
  110. Komai K, Masaharu T, Kitamoto T. [Prion protein coden 129 polymorphism (Val/Met) in a case of sporadic progressive multisystem degenerative disease] Rinsho Shinkeigaku. 1993 Jun;33(6):666-7. Japanese.
  111. Kitamoto T, Iizuka R, Tateishi J. An amber mutation of prion protein in Gerstmann-Straussler syndrome with mutant PrP plaques. Biochem Biophys Res Commun. 1993 Apr 30;192(2):525-31.
  112. Kitamoto T, Ohta M, Doh-ura K, Hitoshi S, Terao Y, Tateishi J. Novel missense variants of prion protein in Creutzfeldt-Jakob disease or Gerstmann-Straussler syndrome. Biochem Biophys Res Commun. 1993 Mar 15;191(2):709-14.
  113. Miyazono M, Iwaki T, Kitamoto T, Shin RW, Fukui M, Tateishi J. Widespread distribution of tau in the astrocytic elements of glial tumors. Acta Neuropathol (Berl). 1993;86(3):236-41.
  114. Muramoto T, Kitamoto T, Tateishi J, Goto I. Successful transmission of Creutzfeldt-Jakob disease from human to mouse verified by prion protein accumulation in mouse brains. Brain Res. 1992 Dec 25;599(2):309-16.
  115. Terao Y, Hitoshi S, Shimizu J, Sakuta M, Kitamoto T. [Gerstmann-Straussler-Scheinker disease with heterozygous codon change at prion protein codon 129] Rinsho Shinkeigaku. 1992 Aug;32(8):880-3. Japanese.
  116. Kitamoto T, Doh-ura K, Muramoto T, Miyazono M, Tateishi J. The primary structure of the prion protein influences the distribution of abnormal prion protein in the central nervous system. Am J Pathol. 1992 Aug;141(2):271-7.
  117. Muramoto T, Kitamoto T, Tateishi J, Goto I. The sequential development of abnormal prion protein accumulation in mice with Creutzfeldt-Jakob disease. Am J Pathol. 1992 Jun;140(6):1411-20.
  118. Kitamoto T, Shin RW, Doh-ura K, Tomokane N, Miyazono M, Muramoto T, Tateishi J. Abnormal isoform of prion proteins accumulates in the synaptic structures of the central nervous system in patients with Creutzfeldt-Jakob disease. Am J Pathol. 1992 Jun;140(6):1285-94.
  119. Miyagawa-Tomita S, Kitamoto T, Momma K, Takao A, Momoi T. Cellular retinoic acid binding protein type II was preferentially localized in medium and posterior parts of the progress zone of the chick limb bud. Biochem Biophys Res Commun. 1992 May 29;185(1):217-23.
  120. Shin RW, Iwaki T, Kitamoto T, Sato Y, Tateishi J. Massive accumulation of modified tau and severe depletion of normal tau characterize the cerebral cortex and white matter of Alzheimer's disease. Demonstration using the hydrated autoclaving method. Am J Pathol. 1992 Apr;140(4):937-45.
  121. Tranchant C, Doh-ura K, Warter JM, Steinmetz G, Chevalier Y, Hanauer A, Kitamoto T, Tateishi J. Gerstmann-Straussler-Scheinker disease in an Alsatian family: clinical and genetic studies. J Neurol Neurosurg Psychiatry. 1992 Mar;55(3):185-7.
  122. Ohgami T, Kitamoto T, Tateishi J. Alzheimer's amyloid precursor protein accumulates within axonal swellings in human brain lesions. Neurosci Lett. 1992 Feb 17;136(1):75-8.
  123. Tateishi J, Kitamoto T, Doh-ura K, Boellaard JW, Peiffer J. Creutzfeldt-Jakob disease with amyloid angiopathy: diagnosis by immunological analyses and transmission experiments. Acta Neuropathol (Berl). 1992;83(5):559-63.
  124. Muramoto T, Kitamoto T, Koga H, Tateishi J. The coexistence of Alzheimer's disease and Creutzfeldt-Jakob disease in a patient with dementia of long duration. Acta Neuropathol (Berl). 1992;84(6):686-9.
  125. Miyazono M, Kitamoto T, Doh-ura K, Iwaki T, Tateishi J. Creutzfeldt-Jakob disease with codon 129 polymorphism (valine): a comparative study of patients with codon 102 point mutation or without mutations. Acta Neuropathol (Berl). 1992;84(4):349-54.
  126. Miyazono M, Kitamoto T, Iwaki T, Tateishi J. Colocalization of prion protein and beta protein in the same amyloid plaques in patients with Gerstmann-Straussler syndrome. Acta Neuropathol (Berl). 1992;83(4):333-9.
  127. Ohgami T, Kitamoto T, Weidmann A, Beyreuther K, Tateishi J. Alzheimer's amyloid precursor protein-positive degenerative neurites exist even within kuru plaques not specific to Alzheimer's disease. Am J Pathol. 1991 Dec;139(6):1245-50.
  128. Kitamoto T, Muramoto T, Mohri S, Doh-Ura K, Tateishi J. Abnormal isoform of prion protein accumulates in follicular dendritic cells in mice with Creutzfeldt-Jakob disease. J Virol. 1991 Nov;65(11):6292-5.
  129. Doh-ura K, Kitamoto T, Sakaki Y, Tateishi J. CJD discrepancy. Nature. 1991 Oct 31;353(6347):801-2.
  130. Miyazono M, Iwaki T, Kitamoto T, Kaneko Y, Doh-ura K, Tateishi J. A comparative immunohistochemical study of Kuru and senile plaques with a special reference to glial reactions at various stages of amyloid plaque formation. Am J Pathol. 1991 Sep;139(3):589-98.
  131. Tomokane N, Kitamoto T, Tateishi J, Sato Y. Immunohistochemical quantification of substance P in spinal dorsal horns of patients with multiple system atrophy. J Neurol Neurosurg Psychiatry. 1991 Jun;54(6):535-41.
  132. Shin RW, Iwaki T, Kitamoto T, Tateishi J. Hydrated autoclave pretreatment enhances tau immunoreactivity in formalin-fixed normal and Alzheimer's disease brain tissues. Lab Invest. 1991 May;64(5):693-702.
  133. Kitamoto T, Muramoto T, Hilbich C, Beyreuther K, Tateishi J. N-terminal sequence of prion protein is also integrated into kuru plaques in patients with Gerstmann-Straussler syndrome. Brain Res. 1991 Apr 5;545(1-2):319-21.
  134. Kitamoto T, Yamaguchi K, Doh-ura K, Tateishi J. A prion protein missense variant is integrated in kuru plaque cores in patients with Gerstmann-Straussler syndrome. Neurology. 1991 Feb;41(2 ( Pt 1)):306-10.
  135. Tranchant C, Doh-Ura K, Steinmetz G, Chevalier Y, Kitamoto T, Tateishi J, Warter JM. [Mutation of codon 117 of the prion gene in Gerstmann-Straussler-Scheinker disease] Rev Neurol (Paris). 1991;147(4):274-8. Review. French.
  136. Ohgami T, Kitamoto T, Shin RW, Kaneko Y, Ogomori K, Tateishi J. Increased senile plaques without microglia in Alzheimer's disease. Acta Neuropathol (Berl). 1991;81(3):242-7.
  137. Tateishi J, Tashima T, Kitamoto T. Practical methods for chemical inactivation of Creutzfeldt-Jakob disease pathogen. Microbiol Immunol. 1991;35(2):163-6.
  138. Shin RW, Kitamoto T, Tateishi J. Modified tau is present in younger nondemented persons: a study of subcortical nuclei in Alzheimer's disease and progressive supranuclear palsy. Acta Neuropathol (Berl). 1991;81(5):517-23.
  139. Kretzschmar HA, Kitamoto T, Doerr-Schott J, Mehraein P, Tateishi J. Diffuse deposition of immunohistochemically labeled prion protein in the granular layer of the cerebellum in a patient with Creutzfeldt-Jakob disease. Acta Neuropathol (Berl). 1991;82(6):536-40.
  140. Doi-Yi R, Kitamoto T, Tateishi J. Immunoreactivity of cerebral amyloidosis is enhanced by protein denaturation treatments. Acta Neuropathol (Berl). 1991;82(4):260-5.
  141. Tateishi J, Kitamoto T, Doh-ura K, Sakaki Y, Steinmetz G, Tranchant C, Warter JM, Heldt N. Immunochemical, molecular genetic, and transmission studies on a case of Gerstmann-Straussler-Scheinker syndrome. Neurology. 1990 Oct;40(10):1578-81.
  142. Doerr-Schott J, Kitamoto T, Tateishi J, Boellaard JW, Heldt N, Lichte C. Immunogold light and electron microscopic detection of amyloid plaques in transmissible spongiform encephalopathies. Neuropathol Appl Neurobiol. 1990 Feb;16(1):85-9.
  143. Doh-ura K, Tateishi J, Kitamoto T, Sasaki H, Sakaki Y. Creutzfeldt-Jakob disease patients with congophilic kuru plaques have the missense variant prion protein common to Gerstmann-Straussler syndrome. Ann Neurol. 1990 Feb;27(2):121-6.
  144. Kitamoto T, Yi R, Mohri S, Tateishi J. Cerebral amyloid in mice with Creutzfeldt-Jakob disease is influenced by the strain of the infectious agent. Brain Res. 1990 Jan 29;508(1):165-7.
  145. Kitamoto T, Mohri S, Tateishi J. Organ distribution of proteinase-resistant prion protein in humans and mice with Creutzfeldt-Jakob disease. J Gen Virol. 1989 Dec;70 ( Pt 12):3371-9.
  146. Kitamoto T, Momoi M, Momoi T. Expression of cellular retinoic acid binding protein II (chick-CRABP II) in the chick embryo. Biochem Biophys Res Commun. 1989 Oct 16;164(1):531-6.
  147. Doh-ura K, Tateishi J, Sasaki H, Kitamoto T, Sakaki Y. Pro----leu change at position 102 of prion protein is the most common but not the sole mutation related to Gerstmann-Straussler syndrome. Biochem Biophys Res Commun. 1989 Sep 15;163(2):974-9.
  148. Shin RW, Ogomori K, Kitamoto T, Tateishi J. Increased tau accumulation in senile plaques as a hallmark in Alzheimer's disease. Am J Pathol. 1989 Jun;134(6):1365-71.
  149. Kitamoto T, Tateishi J, Sawa H, Doh-Ura K. Positive transmission of Creutzfeldt-Jakob disease verified by murine kuru plaques. Lab Invest. 1989 Apr;60(4):507-12.
  150. Ogomori K, Kitamoto T, Tateishi J, Sato Y, Suetsugu M, Abe M. Beta-protein amyloid is widely distributed in the central nervous system of patients with Alzheimer's disease. Am J Pathol. 1989 Feb;134(2):243-51.
  151. Kaneko Y, Kitamoto T, Tateishi J, Yamaguchi K. Ferritin immunohistochemistry as a marker for microglia. Acta Neuropathol (Berl). 1989;79(2):129-36.
  152. Kitamoto T, Momoi T, Momoi M. The presence of a novel cellular retinoic acid-binding protein in chick embryos: purification and partial characterization. Biochem Biophys Res Commun. 1988 Dec 30;157(3):1302-8. Erratum in: Biochem Biophys Res Commun 1989 Feb 28;159(1):371.
  153. Ogomori K, Kitamoto T, Tateishi J, Sato Y, Tashima T. Aging and cerebral amyloid: early detection of amyloid in the human brain using biochemical extraction and immunostain. J Gerontol. 1988 Nov;43(6):B157-62.
  154. Kitamoto T, Tateishi J, Sato Y. Immunohistochemical verification of senile and kuru plaques in Creutzfeldt-Jakob disease and the allied disease. Ann Neurol. 1988 Oct;24(4):537-42.
  155. Matsushima T, Inoue T, Takeshita I, Fukui M, Iwaki T, Kitamoto T. Choroid plexus papillomas: an immunohistochemical study with particular reference to the coexpression of prealbumin. Neurosurgery. 1988 Sep;23(3):384-9.
  156. Tateishi J, Tashima T, Kitamoto T. Inactivation of the Creutzfeldt-Jakob disease agent. Ann Neurol. 1988 Sep;24(3):466.
  157. Tateishi J, Kitamoto T, Hashiguchi H, Shii H. Gerstmann-Straussler-Scheinker disease: immunohistological and experimental studies. Ann Neurol. 1988 Jul;24(1):35-40.
  158. Kitamoto T, Tateishi J. Immunohistochemical confirmation of Creutzfeldt-Jakob disease with a long clinical course with amyloid plaque core antibodies. Am J Pathol. 1988 Jun;131(3):435-43.
  159. Hashiguchi H, Shii H, Kitamoto T, Tateishi J. [An autopsy case of Gerstmann-Straussler-Scheinker's disease with family history] Rinsho Shinkeigaku. 1988 Jun;28(6):681-7. Japanese.
  160. Hori A, Kitamoto T, Tateishi J, Hann P, Friede RL. Focal intracerebral accumulation of a novel type of amyloid protein. An early stage of cerebral amyloidoma? Acta Neuropathol (Berl). 1988;76(2):212-5.
  161. Tashima T, Kitamoto T, Tateishi J, Ogomori K, Nakagaki H. Incidence and characterization of age related amyloid deposits in the human anterior pituitary gland. Virchows Arch A Pathol Anat Histopathol. 1988;412(4):323-7.
  162. Shiiki H, Shimokama T, Yoshikawa Y, Toyoshima H, Kitamoto T, Watanabe T. Renal amyloidosis. Correlations between morphology, chemical types of amyloid protein and clinical features. Virchows Arch A Pathol Anat Histopathol. 1988;412(3):197-204.
  163. Inoue T, Matsushima T, Fukui M, Matsubara T, Kitamoto T. Choroidal epithelial cyst of the cerebral hemisphere. An immunohistochemical study. Surg Neurol. 1987 Aug;28(2):119-22.
  164. Kitamoto T, Ogomori K, Tateishi J, Prusiner SB. Formic acid pretreatment enhances immunostaining of cerebral and systemic amyloids. Lab Invest. 1987 Aug;57(2):230-6.
  165. Tashima T, Kitamoto T, Tateishi J, Sato Y. Congophilia in cerebral amyloidosis is modified by inactivation procedures on slow transmissible pathogens. Brain Res. 1986 Dec 3;399(1):80-6.
  166. Ochiai J, Tobimatsu S, Kobayashi T, Kitamoto T, Kitaguchi T, Furuya H, Goto I, Kuroiwa Y. Nonfamilial prealbumin-type amyloid polyneuropathy. Arch Neurol. 1986 Dec;43(12):1294-5.
  167. Tashima T, Kitamoto T, Tateishi J. Histochemical classification of systemic amyloid fibril proteins. Alkaline guanidine method. Arch Pathol Lab Med. 1986 Oct;110(10):885-8.
  168. Kitamoto T, Tateishi J, Tashima T, Takeshita I, Barry RA, DeArmond SJ, Prusiner SB. Amyloid plaques in Creutzfeldt-Jakob disease stain with prion protein antibodies. Ann Neurol. 1986 Aug;20(2):204-8.
  169. Kitamoto T, Tashima T, Tateishi J. Novel histochemical approaches to the prealbumin-related senile and familial forms of systemic amyloidosis. Am J Pathol. 1986 Jun;123(3):407-12.
  170. Kitamoto T, Hikita K, Tashima T, Tateishi J, Sato Y. Scrapie-associated fibrils (SAF) purification method yields amyloid proteins from systemic and cerebral amyloidosis. Biosci Rep. 1986 May;6(5):459-65.
  171. Tateishi J, Kitamoto T. Membrane filtration of scrapie agent. Lancet. 1986 Jan 25;1(8474):208.
  172. Kitamoto T, Tateishi J, Hikita K, Nagara H, Takeshita I. A new method to classify amyloid fibril proteins. Acta Neuropathol (Berl). 1985;67(3-4):272-8.
  173. Shibasaki H, Nakashima M, Neshige R, Kitamoto T, Kakigi R, Kuroda Y. Neck-abdominal reflex. J Neurol Neurosurg Psychiatry. 1984 Jul;47(7):750-1.
  174. Kitamoto T, Kakigi R, Kuroda Y, Shibasaki H, Nawata H. [Bulbospinal muscular atrophy with endocrinological abnormalities (Kennedy-Alter-Sung syndrome), with special reference to hypothalamo-pituitary dysfunction] Nippon Naika Gakkai Zasshi. 1984 Jun;73(6):831-7. Japanese.
  175. Kitamoto T, Neshige R, Kuroda Y, Noda K, Shibasaki H. [Familial multiple sclerosis: report of two cases with immunogenetic studies] Rinsho Shinkeigaku. 1984 Feb;24(2):159-64. Japanese.
  176. Neshige R, Kuroda Y, Kakigi R, Kitamoto T, Shibasaki H. [Case of alexia with agraphia caused by hematoma of the right temporal lobe] Rinsho Shinkeigaku. 1983 Sep;23(9):804-7. Japanese.